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Sublingual immunotherapy reduces symptoms of asthma and hay fever, systematic review finds

BMJ 2013; 346 doi: http://dx.doi.org/10.1136/bmj.f2056 (Published 02 April 2013) Cite this as: BMJ 2013;346:f2056
  1. Sophie Ramsey
  1. 1BMJ

Researchers have found strong evidence that sublingual immunotherapy improves the symptoms of asthma and moderate evidence that it decreases those of rhinitis and rhinoconjunctivitis.

The researchers, from Johns Hopkins University in Baltimore, carried out a systematic review of the literature to assess the effectiveness and safety of aqueous sublingual immunotherapy for rhinitis and asthma.1 They found 63 randomised controlled trials that compared sublingual immunotherapy with placebo, pharmacotherapy, or other sublingual immunotherapy regimens. These studies …

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