Letters Predicted fracture risk

Authors’ reply to McCloskey and colleagues

BMJ 2013; 346 doi: https://doi.org/10.1136/bmj.f1440 (Published 12 March 2013) Cite this as: BMJ 2013;346:f1440
  1. Mark J Bolland, senior research fellow1,
  2. Rod Jackson, professor of epidemiology1,
  3. Greg Gamble, research fellow1,
  4. Andrew Grey, associate professor of medicine1
  1. 1University of Auckland, Private Bag 92019, Auckland 1142, New Zealand
  1. m.bolland{at}auckland.ac.nz

McCloskey and colleagues seem to misunderstand our analysis and its key messages.1 2 Firstly, fracture risk estimates should be generated for clinically relevant time frames—we suggest a three to five year interval because available interventions are effective within that time frame and it aligns with recommendations for an initial course of osteoporosis treatment. Despite their argument, FRAX generates only …

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