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Spironolactone made no difference to patients with mild diastolic heart failure

BMJ 2013; 346 doi: http://dx.doi.org/10.1136/bmj.f1290 (Published 27 February 2013) Cite this as: BMJ 2013;346:f1290

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Spironolactone failed to improve symptoms, quality of life, or exercise capacity in a recent placebo controlled trial of patients with heart failure caused by diastolic dysfunction. The aldosterone antagonist improved diastolic function and prognostic biomarkers, but not enough to …

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