Letters Hip arthroplasty

Authors’ reply to Jameson and Breusch

BMJ 2012; 345 doi: http://dx.doi.org/10.1136/bmj.e7239 (Published 31 October 2012) Cite this as: BMJ 2012;345:e7239
  1. D J W McMinn, consultant orthopaedic surgeon1,
  2. J Daniel, director of research1,
  3. R B C Treacy, consultant orthopaedic surgeon2,
  4. R D Riley, reader in biostatistics3
  1. 1McMinn Centre, Edgbaston, Birmingham B15 3DP, UK
  2. 2Royal Orthopaedic Hospital, Northfield, Birmingham
  3. 3School of Health and Population Sciences, University of Birmingham, Birmingham
  1. r.d.riley{at}bham.ac.uk

Jameson and Breusch fail to appreciate that the adjusted hazard ratio, indicating higher mortality with cemented total hip replacement (THR), relates to all time points, including the first 60 days, with no indication that this hazard ratio varies over time.1 2 3

We repeatedly emphasised the potential for residual confounding and selection bias.1 Interestingly, when comparing revision rates, the National Joint Registry uses similar survival methods …

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