Re: Fatigue in primary biliary cirrhosis
30 October 2012
With due sympathy to the patient, primary or secondary cirrhosis is not a neoplasm but a benign condition. Due to bile obstruction in any intra-hepatic bile channel, the flattened tubular hepatic acini sandwich between sinusoids, get distended causing pressure atrophy of peri-bile-canalicular hepatocytes, rupture, fibrosis contributed by perisinusoidal linings, and reparative hyperplasia of the surviving hepatocytes. Hepatic fiberoptic cholengiography and sinusoid angiography should be possible in this age of hepatic transplantation. But no reports are visible on any cholengio vascular obstruction removal or plasty in liver for cure of benign obstructive life threatening lesions spreading on the abdomen wall that vessels are blocked.
Competing interests: None declared
JNMC AMU Aligarh India, JNMC AMU Aligarh 202002 India
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