Practice A Patient’s Journey

Neuromuscular degeneration

BMJ 2012; 345 doi: http://dx.doi.org/10.1136/bmj.e6880 (Published 17 October 2012) Cite this as: BMJ 2012;345:e6880

Re: Neuromuscular degeneration

It is of interest that a drug such as a Statin may also cause Neuromuscular Degeneration. One expects a Virus.

At Post Mortem the Pathologist will have noted if there was "demyelination" of elements either of the spinal cord else of peripheral nerves.
That ALS (Amyotrophic Lateral Sclerosis) also known as Motor Neurone Disease was diagnosed yet apparently no therapeutic Vitamin B.12 injections were given.

In other cases of Demyelination, Herpes Ophthalmicus, Bells' Palsy, Vitamin B.12 has been used effectively, since 1954. (Marshall, W. H., Dickie, Hugh. BMJ June 15, 1946 and others.)

In 2006 Demyelination was noted in a case of Motor Neurone Disease (Case 22-2006 Massachusetts General Hospital, reported in the New England Journal of Medicine. Vol.355: 296 -304. July 20, 2006).

Most cases of Demyelination ought to respond to Vitamin B.12, if given very early in every case, whichever, B. 12 is essential for the synthesis of Thymidylate, the base of DNA (deoxyribonucleic acid). The Vitamin plays a biochemical role in the maintenance of Myelin in the nervous system. ( L. Ovesen. DRUGS. 1984, 27. 148) See Martindale's Pharmacopoeia.

Competing interests: No competing interests

06 December 2012
George Y Caldwell
General Practitioner
NIL
31 Balmoral Park, #18-33
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