Christmas 2012: Yesterday’s World

An early British case of neuromyelitis optica (1850)

BMJ 2012; 345 doi: http://dx.doi.org/10.1136/bmj.e6430 (Published 17 December 2012)
Cite this as: BMJ 2012;345:e6430

Get access to this article and all of bmj.com for the next 14 days

Sign up for a 14 day free trial today

Access to the full text of this article requires a subscription or payment. Please log in or subscribe below.

  1. Sven Jarius, neuroimmunologist,
  2. Brigitte Wildemann, head of division
  1. 1Division of Molecular Neuroimmunology, Department of Neurology, University of Heidelberg, Heidelberg, Germany
  1. sven.jarius{at}med.uni-heidelberg.de

The term neuromyelitis optica (Devic’s syndrome) refers to the co-occurrence of acute myelitis and optic neuritis. Regarded for many decades as a clinical variant of multiple sclerosis, neuromyelitis optica has only very recently been recognized as a disease in its own right with distinct pathogenesis, prognosis, and treatment.

While the history of classic multiple sclerosis has been studied extensively, little is known about the early history of neuromyelitis optica. Here we would like to draw readers’ attention to a now forgotten early British case, which appeared in 1850 in the precursor of the BMJ, the Provincial Medical and Surgical Journal, as part of a series of “Brief notes of medical cases,”1 …

Get access to this article and all of bmj.com for the next 14 days

Sign up for a 14 day free trial today

Access to the full text of this article requires a subscription or payment. Please log in or subscribe below.

Article access

Article access for 1 day

Purchase this article for £20 $30 €32*

The PDF version can be downloaded as your personal record

* Prices do not include VAT

THIS WEEK'S POLL