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Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: randomised trial

BMJ 2012; 345 doi: https://doi.org/10.1136/bmj.e6409 (Published 09 October 2012) Cite this as: BMJ 2012;345:e6409

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Re: Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: randomised trial

I would welcome the authors' observations as to the metabolic profiles of participants in this analysis, noting the reservations by a number of other respondents. In particular HDL levels of 1.7, with glucose of 4.7 and health vitamin D levels seem discordant with values seen in everyday practice (in primary and secondary care, underscoring the suggestion that these are innately healthy women). These may in turn have ameliorated the potentially harmful effects of HRT in those taking it.

Competing interests: No competing interests

02 December 2012
A-K Vania
Hospital Practitioner in Cardiology
Department of Cardiology, Glenfield General Hospital
Groby Rd., Leicester LE3 9QP