BMJ 2012; 345 doi: https://doi.org/10.1136/bmj.e5859 (Published 05 September 2012) Cite this as: BMJ 2012;345:e5859
  1. Giri Raj, registrar,
  2. Girish Gupta, consultant,
  3. A Matthews, registrar
  1. 1Lanarkshire Centre for Dermatology, Monklands Hospital, Airdrie ML6 0JS, UK
  1. dr.giriraj{at}yahoo.co.nz

A healthy 45 year old woman presented with an eight month history of a mildly pruritic lesion on her left thigh. Examination showed a red patch, 1 cm in diameter, with no dark pigment. Under dermoscopy, the lesion had no pigment network and had scattered dotted vessels. Histology showed an amelanotic melanoma (Breslow thickness 2.1 mm, pT2a). The lesion underwent wide local excision. Amelanotic melanomas make up 2-8% of malignant melanomas, and their lack of pigment makes diagnosis difficult. These melanomas should be considered in the differential diagnosis of a new, red, evolving patch or nodule.


Cite this as: BMJ 2012;345:e5859


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