Letters PPIs with clopidogrel

Evidence of net benefit of proton pump inhibitors with clopidogrel is lacking in older patients

BMJ 2012; 345 doi: https://doi.org/10.1136/bmj.e5849 (Published 04 September 2012) Cite this as: BMJ 2012;345:e5849
  1. Miles D Witham, senior lecturer in ageing and health1,
  2. Roy Soiza, clinical senior lecturer and consultant geriatrician2,
  3. Ian Logan, specialist registrar in medicine for the elderly3
  1. 1University of Dundee, Ageing and Health, Ninewells Hospital, Dundee DD1 9SY, UK
  2. 2University of Aberdeen, Aberdeen Royal Infirmary, Aberdeen, UK
  3. 3NHS Tayside, Ninewells Hospital
  1. m.witham{at}dundee.ac.uk

Although proton pump inhibitor (PPI) use was not associated with increased risk of myocardial infarction in people on dual antiplatelet treatment,1 we are worried by the linked editorial’s suggestion that PPIs should therefore be prescribed to a wide range of patients on this treatment.2

PPIs have …

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