Are the causes of obesity primarily environmental? No

BMJ 2012; 345 doi: http://dx.doi.org/10.1136/bmj.e5844 (Published 11 September 2012)
Cite this as: BMJ 2012;345:e5844

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Please note that whilst I first heard of the cigarette smoking analogy from George Davey Smith, it originated long before this from Geoffrey Rose (Rose G. Sick individuals and sick populations. Int J Epidemiol 1985;14:32–38 (reprinted Int J Epidemiol 2001;30:427–32)). George has since pointed out that chance would also be a major factor in addition to genetics (Davey Smith G. International Journal of Epidemiology 2011;40:537–562)

Competing interests: None declared

Timothy M Frayling, Scientist

University of Exeter, Magdalen Road, Exeter, EX12LU

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Note from author: my statement "inactivity in children preceded increases in percentage body fat, but increased body fat percentage did not precede reduced physical activity"… is the wrong way around. It should read "inactivity in children did not precede increases in percentage body fat, but increased body fat percentage did precede reduced physical activity".

Apologies for this error and thanks to author of reference article Brad Metcalf for pointing it out.

Competing interests: None declared

Timothy M Frayling, Scientist

University of Exeter, University of Exeter

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