Psychological distress and death from cardiovascular disease

BMJ 2012; 345 doi: http://dx.doi.org/10.1136/bmj.e5177 (Published 31 July 2012)
Cite this as: BMJ 2012;345:e5177

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In Lewis's response (1) to Russ et al's finding (2) of a linear link between psychological distress and mortality, one sentence merits expansion: 'social stresses related to inequalities and socioeconomic status might contribute to the incidence of cardiovascular disease'.
Human families and societies buffer the physiological and psychological effects of stress -- which is ubiquitous -- via Attachment (3). As social animals, humans' response to separation, threat and fear is regulated with the help of a proximate caregiver, their Secure Base. But where care-giving is compromised, although the insecure show little outward sign of (dis)tress, and appear to be 'coping', cortisol responses and HPA axis function are consistently different from their secure counterparts (4), with, as Lewis suggests, potentially lethal long-term consequences
While the self-help CBT approach Lewis advocates has its uses, it runs the risk of perpetuating the very difficulty at the heart of the problem. Prevention calls for a radically relational perspective. At a micro-level, families need encouragement in mutual support and processing of emotional pain. At a societal level flattened inequality gradients and enhanced trust are essential if stress is to be resilience-enhancing rather than death-dealing.

(1) Lewis, G. psychological distress and death from cardiovascular disease. bmj 2012; 354: e5177
(2) Russ, T, et al Association between psychological distress and mortality: individual participant p[oled analysis of 10 prospective cohrt studies. bmj 2012; 345: e4933.
(3) Cassidy, J. & Shaver, P. Handbook of Attachment 2nd edition. 2008. New York: Guilford.
(4) Dozier, M. & Kobac, R. Psychophysiology in attachment interviews. Child Development 1992 63 1473-1480

Competing interests: None declared

jeremy a holmes, Professor of psychological therapies

University of Exeter, University of Exeter EX4 4QG

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To avoid the conceptual barbed wire of "bad stressors", "good stressors", "stress responses" and all the other entanglements these bring, it is more helpful to consider stress in one of two ways. Physiologically, considering environmental challenges to physiological homeostasis, e.g. extreme heat, where the "stressor-stress" ideas might be useful. However, psychologically, stress is best considered as a product of threat arising from the mismatch between perceived demands and perceived resources to meet those demands. Here, the absolute demands and resources are perhaps less important than the perception. It is the perception of mismatch that generates threat (to physical, social, emotional, financial or many other aspects of the self/group), and the appraisal of this threat (primary appraisal) leads to the experience (or not) of stress.

Given that most situations are construed differently by different people; a losing world cup goal might indeed be stressful for the football fan, but not for her or his bored partner, then it is not the situation, but perhaps overbearing attachment to a particular outcome that is the problem. Hence the growing interest in mindfulness.

Perhaps we should all recognize the fundamental tenet of life - things come, they stay a while, then they go away again. It is only when we try to cling to things that are going, or avoid things that are coming that life gets difficult. This is why many studies have indicated that a sense of contentment is a key component of good health.

I promise to get out more.

Competing interests: None declared

Richard Fielding, Clinical Health Psychologist

School of Public Health. , University of Hong Kong, Hong Kong SAR, China

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