Letters Diet and cardiovascular risk

Editorial authors’ reply to Freedhoff

BMJ 2012; 345 doi: https://doi.org/10.1136/bmj.e5109 (Published 06 August 2012) Cite this as: BMJ 2012;345:e5109
  1. Anna Floegel, nutritional epidemiologist1,
  2. Tobias Pischon, professor2
  1. 1Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, 14558 Nuthetal, Germany
  2. 2Molecular Epidemiology Group, Max Delbrück Center for Molecular Medicine Berlin-Buch, Berlin, Germany
  1. anna.floegel{at}dife.de

Freedhoff’s claim that our recommendation for clinicians to advise against the long term use of low carbohydrate-high protein diets because of higher morbidity and mortality from cardiovascular diseases is not evidence based is not correct.1 2

Currently, no randomised controlled trials (RCTs) or meta-analyses of RCTs have investigated the association between low carbohydrate-high protein diets and hard clinical endpoints of cardiovascular disease. Because of this …

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