The idolatry of the surrogate

Type 2 diabetes is a poor example of the overuse of surrogate markers

BMJ 2012; 344 doi: http://dx.doi.org/10.1136/bmj.e735 (Published 31 January 2012)
Cite this as: BMJ 2012;344:e735

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  1. Ian Dickson, general practitioner1
  1. 1Springwell Medical Centre, Edinburgh EH11 2JL, UK
  1. iandickson{at}blueyonder.co.uk

As a general practitioner with a special interest in type 2 diabetes, I believe that Yudkin and colleagues have chosen the wrong disease to argue the dangers of the overuse of surrogate markers.1 They do not mention the UK Prospective Diabetes Study, which had hard clinical end points and emphasised the importance of lowering blood pressure to decrease hard cardiovascular end points such as myocardial …

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