Letters Beneficial drug reactions

System rather than target driven approach needed to discover beneficial drug effects

BMJ 2012; 344 doi: http://dx.doi.org/10.1136/bmj.e543 (Published 24 January 2012) Cite this as: BMJ 2012;344:e543
  1. Jeffrey K Aronson, clinical pharmacologist1
  1. 1University of Oxford, Department of Primary Health Care, Oxford OX1 2ET, UK
  1. jeffrey.aronson{at}clinpharm.ox.ac.uk

Parle and colleagues highlight some of the many examples of chance findings of beneficial effects of drugs.1 It is already possible to mine pharmacovigilance databases—for example, that of the Uppsala Monitoring Centre, which contains upwards of 6 million reports of suspected reactions pooled from national databases …

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