- Deborah Cohen, investigations editor
- 1BMJ, London WC1H 9JR, UK
- dcohen{at}bmj.com
Researchers working on the latest Cochrane Collaboration meta-analysis of the evidence on oseltamivir (Tamiflu) have claimed that the drug’s manufacturer is still denying them access to full trial data. This is despite Roche, the Swiss company behind oseltamivir, pledging in the BMJ two years ago that it would make “full study reports” available.1 As a consequence, confusion still surrounds the evidence on oseltamivir and guidance on how doctors should prescribe it.
The latest Cochrane review on oseltamivir, a drug on which governments around the world have spent billions of pounds, is published today (18 January). But the Cochrane reviewers have received only part of the clinical study reports—the summary of the study methods and the results. The company says this is enough for the Cochrane group to conduct their review, but Cochrane denies this.
Meanwhile, GlaxoSmithKline—the makers of the less popular antiviral drug zanamivir (Relenza)—have offered individual patient data. When the BMJ asked Roche why it was refusing to make its data available, despite GSK’s promises, it said it refused to answer until it had had the chance to see the full Cochrane review.
Clinicians can be forgiven for being confused about what the evidence on oseltamivir says. Last September, the UK Department of Health announced that in the event …
Sign in
Personal subscribers, sign in here:
Article access
Article access for 1 day
Purchase this article for £20 $30 €32*
The PDF version can be downloaded as your personal record
CiteULike
Connotea
Del.icio.us
Digg
Facebook
Reddit
Technorati
Twitter
Stumbleupon
Rapid responses
Latest Responses
Hormone replacement therapy - psychiatric aspects
Published 22 February 2012
Re: Assaulting alternative medicine: worthwhile or witch hunt?
Published 22 February 2012
Re: Raised inflammatory markers
Published 22 February 2012
Re: Assaulting alternative medicine: worthwhile or witch hunt?
Published 22 February 2012
Re: Improving the delivery of safe and effective healthcare in low and middle income countries
Published 22 February 2012
Most responses
Assaulting alternative medicine: worthwhile or witch hunt? (12 responses)
Published 15 Feb 2012
Shared decision making: really putting patients at the centre of healthcare (8 responses)
Published 27 Jan 2012
Why legislation is necessary for my health reforms (8 responses)
Published 1 Feb 2012
Raised inflammatory markers (7 responses)
Published 3 Feb 2012
Independence in disciplinary proceedings against doctors (5 responses)
Published 24 Jan 2012