Are we nearly there with tranexamic acid?

BMJ 2012; 344 doi: http://dx.doi.org/10.1136/bmj.e3665 (Published 24 May 2012)
Cite this as: BMJ 2012;344:e3665
  1. Fiona Godlee, editor, BMJ
  1. fgodlee{at}bmj.com

It’s the week of the annual BMJ Group Improving Health Awards (http://groupawards.bmj.com). By the time you read this we’ll know who has won which of the 12 awards and why. Last year we awarded research paper of the year to the CRASH trialists for their large multicountry placebo controlled randomised trial of tranexamic acid after trauma (Lancet 2010;376:23-32). They found a significant reduction in bleeding and mortality in patients given the drug. At the awards event one of the senior authors, Ian Roberts, told me of his frustration that, despite cumulative evidence of the effectiveness of tranexamic acid in reducing the need for blood transfusion …

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