Prescribing bevacizumab off-label contravenes GMC advice

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Graham Kyle, consultant ophthalmologist1

¹Liverpool L1 9AR, UK

grahamkyle33{at}gmail.com

Jackson and Kirkpatrick recommend adopting cheaper bevacizumab over more expensive ranibizumab to treat wet age related macular degeneration.1 However, their cost projections “do not consider any potential differences in safety, medicolegal risk, treatment burden, or patient preference . . . .”

The medicolegal risks of such an adoption are considerable, not least for …