Letters Plotting surrogate outcomes

Arrow plots show results of meta-analyses of surrogate and clinical outcomes

BMJ 2011; 343 doi: https://doi.org/10.1136/bmj.d6126 (Published 27 September 2011) Cite this as: BMJ 2011;343:d6126
  1. Robert Badgett, professor1,
  2. Fanglong Dong, research assistant professor2,
  3. KoKo Aung, associate professor of medicine3
  1. 1Department of Internal Medicine and Department of Preventive Medicine and Public Health, Kansas University School of Medicine—Wichita, 1010 N Kansas, Wichita, KS 67214-3199, USA
  2. 2Department of Preventive Medicine and Public Health, Kansas University School of Medicine—Wichita, Wichita, KS 67214-3199, USA
  3. 3University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, Mail Code 7879, San Antonio, TX 78229-3901, USA
  1. rbadgett{at}kumc.edu

Boussageon and colleagues conclude that relying on surrogate end points for treating people with type 2 diabetes is a fallacy.1 Forest plots in meta-analyses do not, however, show well the relation between a surrogate outcome such as a biomarker and a clinical …

View Full Text

Sign in

Log in through your institution

Free trial

Register for a free trial to thebmj.com to receive unlimited access to all content on thebmj.com for 14 days.
Sign up for a free trial

Subscribe