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Cancer patients were enrolled in “fraudulent” research, US lawsuit alleges

BMJ 2011; 343 doi: http://dx.doi.org/10.1136/bmj.d5986 (Published 21 September 2011) Cite this as: BMJ 2011;343:d5986
  1. Clare Dyer
  1. 1BMJ

Duke University, in North Carolina, is facing two lawsuits alleging that patients with cancer were exposed to unnecessary and harmful chemotherapy after being enrolled in “fraudulent” clinical trials that were based on flawed research.

The trials, which have been discontinued, were based on research by the oncologist Anil Potti into a technique that uses gene expression to predict which chemotherapy would be best for an individual patient with lung or breast cancer.

Dr Potti has resigned and six of his research articles—in the New England Journal of Medicine, Nature Medicine, Lancet Oncology, the Journal of Clinical Oncology, Blood, and PLoS One—have been retracted in recent …

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