Endgames Statistical Question

Survival (time to event) data: censored observations

BMJ 2011; 343 doi: http://dx.doi.org/10.1136/bmj.d4816 (Published 03 August 2011) Cite this as: BMJ 2011;343:d4816
  1. Philip Sedgwick, senior lecturer in medical statistics
  1. 1Section of Medical and Healthcare Education, St George’s, University of London, Tooting, London, UK
  1. p.sedgwick{at}sgul.ac.uk

Researchers assessed the effectiveness of low dose high frequency ultrasound when combined with standard care in healing venous leg ulcers that had previously been hard to heal. Ultrasound was given for 12 weeks, after which participants returned to standard care alone. A multicentre randomised controlled trial was performed. Control treatment was standard care.1

Trial participants were recruited if they had at least one venous leg ulcer of greater than six months’ duration or greater than 5 cm2 in area, and an ankle brachial pressure index greater than 0.8. In total, 168 people were randomised to ultrasound and standard care, with 169 allocated to standard care alone. Each trial participant was treated for a total of 12 …

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