Samarthji LalBMJ 2011; 342 doi: https://doi.org/10.1136/bmj.d685 (Published 31 January 2011) Cite this as: BMJ 2011;342:d685
- Maureen Kiely
Samarthji Lal (“Sam”) cofounded the Douglas Mental Health University Institute Research Centre in Montreal in 1979 and, one year later, established Canada’s first brain bank at the same institution. Lal is credited with introducing apomorphine and clonidine as pharmacological probes of dopaminergic and alpha-2 adrenergic function in clinical research. He was the first to demonstrate that a centrally acting agent, apomorphine, induced penile erections in normal subjects and in patients with impotence of diverse causes. In 2001 apomorphine was marketed in Europe and Asia as a treatment for impotence under the trade name Uprima.
The third son of Dr Yadu Nandan Lal, a St Andrews trained general practitioner …