Institute of Medicine respondsBMJ 2011; 342 doi: http://dx.doi.org/10.1136/bmj.d4046 (Published 28 June 2011) Cite this as: BMJ 2011;342:d4046
- J Christopher Gallagher, professor of medicine, director1,
- Clifford Rosen, professor of medicine2
- 1Bone Metabolism Unit, Creighton University Medical School, Omaha, NE, USA
- 2Tufts University School of Medicine, Boston, MA, USA
The Institute of Medicine (IOM) criticised inconsistencies and misrepresentations of data in the meta-analysis of vitamin D and fall prevention by Bischoff-Ferrari and colleagues.1 2 The authors replied to the IOM,3 and we respond to them as members of the IOM committee.
In assessing the dose-response relation between vitamin D dose, serum 25-hydroxyvitamin D concentration, and risk of a fall the authors opted to compare subgroups of studies above or below a cut off point of vitamin D dose and serum 25 hydroxyvitamin …