Authors’ replyBMJ 2011; 342 doi: http://dx.doi.org/10.1136/bmj.d3350 (Published 31 May 2011) Cite this as: BMJ 2011;342:d3350
- Lisa Hartling, assistant professor1,
- Ricardo M Fernandes, PhD student2,
- Liza Bialy, project coordinator1,
- Andrea Milne, research assistant1,
- David Johnson, professor3,
- Amy Plint, associate professor4,
- Terry P Klassen, professor5,
- Ben Vandermeer, biostatistician1
- 1Alberta Research Centre for Health Evidence, Department of Pediatrics, University of Alberta, 11402 University Avenue, Edmonton, AB, Canada T6G 2J3
- 2Gulbenkian Program for Advanced Medical Education; Child and Family Department, Hospital de Santa Maria; Clinical Pharmacology and Therapeutics, Institute of Molecular Medicine, Lisbon, Portugal
- 3Department of Pediatrics and Department of Physiology and Pharmacology, University of Calgary and Alberta Children’s Hospital, Calgary, AB, Canada
- 4Department of Pediatrics and Department of Emergency Medicine, University of Ottawa, Ottawa, ON, Canada
- 5Manitoba Institute of Child Health, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada
Our paper was not a Cochrane review,1 although it builds on several and adds a network analysis.
To minimise bias we used a predefined protocol developed with physicians and stakeholders which had predefined inclusion criteria for population, interventions, and outcomes.
A priori we decided to focus on first time wheezers. The first episode of wheezing may prove to be the first manifestation of a range …
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