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Treat HIV quickly to prevent infection of spouse, study of heterosexuals shows

BMJ 2011; 342 doi: https://doi.org/10.1136/bmj.d3024 (Published 16 May 2011) Cite this as: BMJ 2011;342:d3024
  1. Bob Roehr
  1. 1Washington, DC

Antiretroviral treatment of people infected with HIV dramatically reduces the risk that they transmit the infection to their spouse, indicate the early results of a large study of serodiscordant heterosexual couples conducted around the world.

Previous observational studies had strongly indicated that treatment would reduce the risk of transmission. The randomised controlled study, known as HPTN (HIV Prevention Trials Network) 052 and funded by the US National Institute of Allergy and Infectious Diseases, was conducted in nine countries in Africa, Asia, and South America. It enrolled 1763 couples where 890 men and 873 women were HIV positive. They all had a CD4 T …

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