Letters Carbamazepine in pregnancy

Levetiracetam and lamotrigine are better options

BMJ 2011; 342 doi: https://doi.org/10.1136/bmj.d279 (Published 25 January 2011) Cite this as: BMJ 2011;342:d279
  1. Ivan Iniesta, consultant neurologist1
  1. 1Walton Centre NHS Foundation Trust, Liverpool L9 7LJ, UK
  1. ivan.iniesta{at}thewaltoncentre.nhs.uk

Nulman’s statement that carbamazepine is the antiepileptic drug of choice in pregnancy does not reflect evidence based clinical practice.1 Carbamazepine is contraindicated in one of the most common epilepsies—idiopathic generalised epilepsy.

Randomised controlled trials have shown lamotrigine to be the best choice for partial onset epilepsies in the general population because …

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