Letters
Suicide and antidepressants
Beware extrapolation from ecological data
BMJ 2010; 341 doi: https://doi.org/10.1136/bmj.c6844 (Published 30 November 2010) Cite this as: BMJ 2010;341:c6844- Tarek A Hammad, associate director of epidemiology1,
- Andrew D Mosholder, senior medical epidemiologist1
- 1Division of Epidemiology, Office of Surveillance and Epidemiology, Center for Drug Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Avenue, Silver Spring, MD 20993, USA
- Tarek.Hammad{at}fda.hhs.gov
Identification of an association between antidepressant drugs and suicidal thinking and behaviour in adolescents in 2004, and the regulatory warnings that followed, sparked a debate on the potential for discouraging appropriate use of antidepressant drugs,1 2 3 with the unintended consequence of eventually exposing more patients to the suicide risk of untreated depression.4 These concerns were strengthened by …
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