Letters Glucosamine and osteoarthritis

Conclusions not supported by methods and results

BMJ 2010; 341 doi: http://dx.doi.org/10.1136/bmj.c6338 (Published 09 November 2010) Cite this as: BMJ 2010;341:c6338
  1. Giampaolo Giacovelli, head, department of biostatistics1,
  2. Lucio C Rovati, chief scientific officer1
  1. 1Rottapharm Madaus, 20052 Monza, Italy
  1. giampaolo.giacovelli{at}rottapharm.com

Wandel and colleagues produced another meta-analysis of glucosamine in osteoarthritis without new evidence when more comprehensive ones showed that the quality controlled product of glucosamine sulphate for prescription is effective.1 2 3 4

Their statistical methods are so complex that many are mystified by whether the conclusions make sense.5 Indeed, we verified that a conventional approach gives identical results to their network meta-analysis …

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