Letters Length of treatment

Three questions for prescribers

BMJ 2010; 341 doi: http://dx.doi.org/10.1136/bmj.c5013 (Published 15 September 2010) Cite this as: BMJ 2010;341:c5013
  1. Jeffrey K Aronson, clinical pharmacologist1,
  2. Robin E Ferner, consultant clinical pharmacologist2
  1. 1University of Oxford, Oxford OX3 7DQ
  2. 2School of Clinical and Experimental Medicine, University of Birmingham, Birmingham B15 2TT
  1. jeffrey.aronson{at}clinpharm.ox.ac.uk

    Craig and colleagues suggest three questions to answer before introducing a therapeutic intervention:

    • •Does it do more good than harm?

    • •How intense should it be?

    • •For how long should it be given?1

    The first question illustrates a difficulty with evidence based medicine, which is generally based on the results of studies in populations. These are not always relevant …

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