BMJ 2010; 340 doi: http://dx.doi.org/10.1136/bmj.c881 (Published 18 February 2010) Cite this as: BMJ 2010;340:c881

A patient’s anxiety is thought to affect the dose of propofol needed to induce loss of consciousness for a general anaesthetic, but studies have reported conflicting results, which might be accounted for by the haemodynamic effects of anxiety (heart rate and cardiac output). A study of 45 women undergoing gynaecological surgery reported a significant relation between heart rate and propofol dose when consciousness was lost, but not between anxiety and propofol dose. Perioperative anxiety, however, was significantly related to increased heart rate (Anesthesia and Analgesia 2010;110:89-93, doi:10.1213/ANE.0b013e3181c5bd11).

Patients of South Asian origin admitted to London hospitals for strokes appear to have different risk factors than their white counterparts. They showed a higher frequency of hypertension, diabetes, and hyperlipidaemia than white patients. They also tended to be younger and to smoke less than the white group. The authors of a study in QJM say that South Asians comprise the largest ethnic minority population in the UK and recommend that secondary prevention programmes should be tailored for this community (2010;103:17-21, doi:10.1093/qjmed/hcp148). …

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