Researchers identify potential broad spectrum antiviral drugBMJ 2010; 340 doi: http://dx.doi.org/10.1136/bmj.c800 (Published 10 February 2010) Cite this as: BMJ 2010;340:c800
- Bob Roehr
- 1Washington, DC
Researchers have identified a potential new antiviral agent that is effective against common flu, rare Ebola virus, and a host of viruses in between, including HIV.
The small molecule, named LJ001, targets lipids in enveloped viruses and prevents their entry into cells during the fusion process in which a virus enters a cell, say researchers in a paper published online in the Proceedings of the National Academy of Sciences of the United States of America (doi:10.1073/pnas.0909587107).
The research began with the screening of a library of 30 000 molecules for activity against the deadly Nipah virus by a team …