Endgames Statistical Question

Allocation concealment

BMJ 2010; 340 doi: http://dx.doi.org/10.1136/bmj.c537 (Published 04 February 2010) Cite this as: BMJ 2010;340:c537
  1. Philip Sedgwick, senior lecturer in medical statistics
  1. 1Centre for Medical and Healthcare Education, St George’s, University of London, Tooting, London SW17 0RE
  1. p.sedgwick{at}sgul.ac.uk

    A randomised controlled trial investigated whether an exercise programme increased activity levels in women. Intervention consisted of brief physical activity with regular support that was led by nurses. Control participants received usual care. The order in which participants were allocated to treatment was contained in sequentially numbered opaque envelopes. A researcher not involved in recruitment generated the sequence by computer. Following written informed consent and baseline measurements, treatment allocation was revealed by a nurse not involved in future assessments. …

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