Part of beneficial host response?BMJ 2010; 340 doi: https://doi.org/10.1136/bmj.c450 (Published 26 January 2010) Cite this as: BMJ 2010;340:c450
- Garth Dixon, consultant microbiologist and honorary senior lecturer1,
- Clare Booth, research assistant2,
- Elizabeth Price, honorary consultant microbiologist3,
- Roger Westran, senior biomedical scientist3,
- Malcolm Turner, professor of molecular immunology2,
- Nigel Klein, professor of infection and immunity1
- 1Infectious Diseases and Microbiology Unit, Institute of Child Health, University College London, London WC1N 1EH
- 2Immunobiology Unit, Institute of Child Health, University College London, London WC1N 1EH
- 3Department of Medical Microbiology, Barts and the London NHS Trust, Pathology Pharmacy Building, London E1 2ES
Fowler comments on the value of a raised temperature to combat flu.1 Fever may also be necessary for optimal defence against bacterial infections.2 We explored this possibility for meningococcal disease.
We diluted a suspension of an isolate of Neisseria meningitidis B to approximately 109 colony forming units/ml. We inoculated 500 µl suspension into supplemented proteose peptone 9.5 ml in duplicate and incubated one tube of …
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