MinervaBMJ 2010; 340 doi: https://doi.org/10.1136/bmj.c2888 (Published 04 June 2010) Cite this as: BMJ 2010;340:c2888
Two drugs—labetalol and methyldopa—commonly taken for high blood pressure during pregnancy may negatively affect children’s functional development (BJOG 2010; published online 19 May, doi:10.1111/j.1471-0528.2010.02568.x). Exposure to labetalol in utero seemed to be associated with attention deficit hyperactivity disorder in children of primary school age, while prenatal exposure to methyldopa was associated with sleeping problems. The small Dutch study of 202 children compared those born to women who took medication with those whose mothers had bed rest only. A statement from the RCOG says “interpret with caution”—much larger prospective studies are needed to test the hypothesis fully.
Families in Uganda affected by HIV say they are happy with the retroviral treatment that relatives receive, but they worry about how to muster sufficient labour for subsistence farming. Sustaining the household was of paramount concern to family members, and illness and treatment for HIV in relatives can affect the survival of the whole family. According to many people interviewed for a qualitative study in AIDS Care, many families in Uganda are pleased that treatment is …
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