PlacebosBMJ 2010; 340 doi: https://doi.org/10.1136/bmj.c247 (Published 21 January 2010) Cite this as: BMJ 2010;340:c247
- Philip Sedgwick, senior lecturer in medical statistics
- 1Centre for Medical and Healthcare Education, St George’s, University of London, Tooting, London SW17 0RE
Researchers undertook a randomised, double blind, placebo controlled trial to assess whether calcium supplementation was associated with adverse cardiovascular events.1 Healthy postmenopausal women were recruited and randomly assigned to receive five tablets a day of either 200 mg of elemental calcium or identical placebo. The occurrence of adverse cardiovascular events over a five year period was recorded. Calcium supplementation in healthy postmenopausal women was associated with increased rates of adverse cardiovascular events.
Which of the following statements, if any, are true?
a) The placebo was an inert treatment with no …