- Richard Lilford, professor of clinical epidemiology1,
- Peter Pronovost, anaesthesiologist and critical care physician2
- 1Public Health, Epidemiology and Biostatistics, University of Birmingham, Edgbaston, Birmingham B15 2TT
- 2Department of Anesthesiology and Critical Care Medicine, Quality and Safety Research Group, Johns Hopkins University School of Medicine, 1909 Thames St, Baltimore, MD 21231, USA
- Correspondence to: R Lilford r.j.lilford{at}bham.ac.uk
- Accepted 2 April 2010
Death is the most tractable outcome of care— it is easily measured, of undisputed importance to everyone, and is common in hospital settings. Mortality rates, especially overall hospital mortality rates, have therefore become the natural focus for measurement of clinical quality. In England a high death rate “attracted the attention of the [Healthcare Commission] (HCC) and caused it to launch its investigation” into the Mid Staffordshire NHS Foundation Trust.1
So what is the problem with measuring clinical performance by comparing hospital mortality rates and what alternatives can we offer?
Hospital mortality as a measure of quality: scientific issues
The problem stems from the ratio of a low signal (preventable deaths) in relation to high noise (deaths from other causes). A common but naive response is to argue that risk adjustment to produce a standardised mortality ratio (SMR) solves this problem. However, the idea that a risk adjustment model separates preventable from inevitable deaths is wrong for two reasons.
Firstly, risk adjustment can only adjust for factors that can be identified and measured accurately.2 Randomised trials are preferable to observational studies with statistical controls for this reason. The error of attributing differences in risk adjusted mortality to differences in quality of care is the “case-mix adjustment fallacy”.3
Secondly, risk adjustment can exaggerate the very bias that it is intended to reduce. This counterintuitive effect is called the “constant risk fallacy” and it arises when the risk associated with the variable on which adjustment is made varies across the units being compared.4 For example, if diabetes is a more powerful prognostic factor in Glasgow than in Four Oaks, then adjusting …
Sign in
Personal subscribers, sign in here:
Article access
Article access for 1 day
Purchase this article for £20 $30 €32*
The PDF version can be downloaded as your personal record
CiteULike
Connotea
Del.icio.us
Digg
Facebook
Reddit
Technorati
Twitter
Stumbleupon
Rapid responses
Latest Responses
The decline in the breast cancer incidence is 1.2% and it is not significant.
Published 10 February 2012
'twas ever thus
Published 10 February 2012
The value of historic human remains
Published 10 February 2012
In Praise of British Literature
Published 10 February 2012
Is real shared decision making possible?
Published 10 February 2012
Most responses
Does anyone understand the government’s plan for the NHS? (17 responses)
Published 17 Jan 2012
Bad medicine: medical nutrition (15 responses)
Published 18 Jan 2012
Shared decision making: really putting patients at the centre of healthcare (7 responses)
Published 27 Jan 2012
Why legislation is necessary for my health reforms (7 responses)
Published 1 Feb 2012
Search for evidence goes on (5 responses)
Published 17 Jan 2012