The lively response to last month’s editorial on chronic fatigue syndrome (BMJ 2010;340:c738, doi:10.1136/bmj.c738) brings home the inadequacy of our current understanding of this condition, or group of conditions. The responses from patients, carers, and clinicians remind us that we remain largely in the dark about its causes and prognosis, there are no accepted diagnostic tests, and treatment options are limited (www.bmj.com/cgi/eletters/340/feb11_1/c738). Sufferers must also deal with social and (if they are doctors) professional stigmatisation, as dermatologist Stephanie Munn experienced (doi:10.1136/bmj.c1179).

Little wonder if many who live or work with chronic fatigue syndrome leapt at the news last October that scientists in Nevada had found a “highly significant association” between the condition and …