Letters Metformin and lactic acidosis

NSAIDs and renin-angiotensin-aldosterone system

BMJ 2009; 339 doi: http://dx.doi.org/10.1136/bmj.b5567 (Published 23 December 2009) Cite this as: BMJ 2009;339:b5567
  1. Ajith James, consultant nephrologist1
  1. 1Barts and the London NHS Trust
  1. ajith.James{at}bartsandthelondon.nhs.uk

    In their lesson of the week Fitzgerald and colleagues highlight lactic acidosis as a rare but potentially hazardous complication of metformin.1 However, the fundamental problem was not continuing metformin treatment but introducing treatment with non-steroidal anti-inflammatory drugs …

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