Varenicline and suicide

Risk of psychiatric side effects with varenicline

BMJ 2009; 339 doi: http://dx.doi.org/10.1136/bmj.b4964 (Published 1 December 2009)
Cite this as: BMJ 2009;339:b4964

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  1. Thomas J Moore, senior scientist1,
  2. Curt D Furberg, professor2
  1. 1Institute For Safe Medication Practices, Alexandria, VA 22314, USA
  2. 2Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1063, USA
  1. tmoore{at}ismp.org

    Gunnell and colleagues report “no clear evidence” that varenicline, a drug to aid smoking cessation, is associated with suicidal behaviours.1 This finding is directly contradicted by a strong signal seen in the most recent data from the UK’s yellow card system (table).2

    View this table:

    Numbers of psychiatric symptoms reported under UK yellow card …

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