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Full data from Thai HIV vaccine study show no significant protective effect

BMJ 2009; 339 doi: https://doi.org/10.1136/bmj.b4370 (Published 23 October 2009) Cite this as: BMJ 2009;339:b4370
  1. Bob Roehr
  1. 1Washington, DC

    Disclosure of the full data from the trial of an HIV vaccine in Thailand shows that although there was a trend towards the prevention of HIV among vaccine recipients this did not reach statistical significance.

    The study sparked controversy in September when the authors released incomplete trial results, in which one type of analysis showed the vaccine reduced infection rate by a third (BMJ 2009;339:b3963, doi:10.1136/bmj.b3963). Critics said that they should have waited until complete data were available for release.

    The additional data were presented at the AIDS Vaccine 2009 conference in Paris on 20 October and simultaneously published in the New England Journal of …

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