Bespoke cohort studies neededBMJ 2009; 339 doi: http://dx.doi.org/10.1136/bmj.b3512 (Published 01 September 2009) Cite this as: BMJ 2009;339:b3512
- Richard Morris, professor of medical statistics and epidemiology1,
- Irene Petersen, MRC training fellow1,
- Louise Marston, research statistician1,
- Kate Walters, clinical senior lecturer1,
- James Carpenter, reader in medical and social statistics2,
- Irwin Nazareth, professor of primary care1
- 1Department of Primary Care and Population Health, University College London, Royal Free Campus, London NW3 2PF
- 2Medical Statistics Unit, London School of Hygiene and Tropical Medicine, London WC1E 7HT
Despite Collins and Altman’s re-analysis of data from the THIN database to validate the QRISK equation for predicting cardiovascular disease,1 adoption of QRISK in primary care is premature because key issues about the handling of missing data and the use of social deprivation indices remain unresolved.
Collins and Altman again highlight that …
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