Study designBMJ 2009; 338 doi: http://dx.doi.org/10.1136/bmj.b2381 (Published 17 June 2009) Cite this as: BMJ 2009;338:b2381
- Philip Sedgwick, senior lecturer in medical statistics
- 1Centre for Medical and Healthcare Education, St George’s, University of London, London SW17 0RE
A clinical trial investigated the effectiveness of topical versus oral ibuprofen for chronic knee pain in people over 50. In designing a trial to decide the best treatment approach, which answer best describes how confounding could be minimised?
a) Double blind trial
b) Intention to treat analyses
c) Matching by age and sex
d) Randomisation of research participants
d—Randomisation means that all individuals have the same probability of being allocated to …
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