HRT in premature menopauseBMJ 2008; 337 doi: https://doi.org/10.1136/bmj.a1668 (Published 16 September 2008) Cite this as: BMJ 2008;337:a1668
- Margaret C P Rees, reader in reproductive medicine, University of Oxford1
Grant’s blanket statement,1 based on the WISDOM study,2 that “it would be irresponsible to think that any use of hormone replacement therapy (HRT) is justifiable” will confuse those dealing with women with early ovarian failure in their 20s and 30s. National guidelines recommend the use of HRT in this group until the average age of the natural menopause in the early 50s.3 The results of the WISDOM study, which randomised women with a mean age of 63.8 years, should not be extrapolated to them.
Cite this as: BMJ 2008;337:a1668
Competing interests: None declared.
Log in using your username and password
Log in through your institution
Register for a free trial to thebmj.com to receive unlimited access to all content on thebmj.com for 14 days.
Sign up for a free trial