Intended for healthcare professionals

  1. Research
  2. Developing and...
  3. Developing and evaluating complex interventions: the new Medical Research Council guidance
Research Methods & Reporting

Developing and evaluating complex interventions: the new Medical Research Council guidance

BMJ 2008; 337 doi: https://doi.org/10.1136/bmj.a1655 (Published 29 September 2008) Cite this as: BMJ 2008;337:a1655

Related articles

See more

Cited by...

  • Mixed-methods feasibility outcomes for a novel ACT-based video game 'ACTing Minds to support mental health
  • Decentralising chronic disease management in sub-Saharan Africa: a protocol for the qualitative process evaluation of community-based integrated management of HIV, diabetes and hypertension in Tanzania and Uganda
  • Health literacy interventions for informal caregivers: systematic review
  • What are the views of adults with an intellectual disability (AWID), carers and healthcare professionals on a community falls management programme for AWID: a qualitative interview study in the UK
  • Co-design and refinement of an optimised antenatal education session to better inform women and prepare them for labour and birth
  • Pioglitazone and barriers to effective post-stroke comorbidity management in stroke survivors with diabetes
  • Effectiveness of CO-OP group intervention for children with developmental coordination disorder: single-case experimental design study protocol
  • Lessons Learned From the Implementation of a School-Based Sexual Health Education Program for Adolescent Girls in Cape Town, South Africa
  • Self-Management Analysis in Chronic Conditions (SMACC) checklist: an international consensus-based tool to develop, compare and evaluate self-management support programmes
  • Impact of an Acceptance and Commitment Therapy programme on HbA1c, self-management and psychosocial factors in adults with type 1 diabetes and elevated HbA1c levels: a randomised controlled trial
  • What are the features of high-performing quality improvement collaboratives? A qualitative case study of a state-wide collaboratives programme
  • Hospital-based caregiver intervention for people following hip fracture surgery (HIP HELPER): multicentre randomised controlled feasibility trial with embedded qualitative study in England
  • What does 'following the guidance mean in an era of increasingly pluralistic guidance for the development, evaluation and implementation of interventions?
  • University hospital center for palliative and supportive care
  • Prioritising and planning scale-up research projects targeting non-communicable diseases: a mixed-method study by the Global Alliance for Chronic Diseases upscaling working group
  • Ukraine Trauma Project: the feasibility of introducing advanced trauma-care skills to frontline emergency medical services responders
  • What works for and what hinders deimplementation of low-value care in emergency medicine practice? A scoping review
  • Effectiveness of an individually tailored complex intervention to improve activities and participation in nursing home residents with joint contractures (JointConEval): a multicentre pragmatic cluster-randomised controlled trial
  • Wellbeing After Stroke (WAterS): feasibility testing of a co-developed Acceptance and Commitment Therapy (ACT) intervention, to support psychological adjustment after stroke
  • Training-of-trainers program for community health workers involved in an innovative and community-based intervention among goldminers in the Guiana Shield: a quality and effectiveness evaluation
  • Embedding nurse home visiting in universal healthcare: 6-year follow-up of a randomised trial
  • Implementing a package of essential non-communicable diseases interventions in low- and middle-income countries: a realist review protocol
  • Development and content of a community-based reablement programme (I-MANAGE): a co-creation study
  • The STAIR OF KNOWLEDGE--a codesigned intervention to prevent pressure ulcers, malnutrition, poor oral health and falls among older persons in nursing homes in Sweden: development of a complex intervention
  • Assessing a nurse-assisted eHealth intervention posthospital discharge in adult patients with non-communicable diseases: a protocol for a feasibility study
  • How capacity building of district health managers has been designed, delivered and evaluated in sub-Saharan Africa: a scoping review and best fit framework analysis
  • The Colorectal cancer RISk Prediction (CRISP) trial: a randomised controlled trial of a decision support tool for risk-stratified colorectal cancer screening
  • How and why educational interventions work to increase knowledge of delirium among healthcare professionals in nursing homes: a protocol for a realist review
  • Effects of a clinical decision support system and patient portal for preventing medication-related falls in older fallers: Protocol of a cluster randomized controlled trial with embedded process and economic evaluations (ADFICE_IT)
  • Capacity building of district health management teams in the era of provincial health administration reform in the Democratic Republic of Congo: a realist evaluation protocol
  • Further development and feasibility randomised controlled trial of a digital programme for adolescent depression, MoodHwb: study protocol
  • Multimodal prehabilitation service for patients with colorectal cancer: the challenges of implementation
  • Patient perceptions and experiences with medication-related activities in the emergency department: a qualitative study
  • Role development, implementation and evaluation of nurse practitioners in a Belgian university hospital: a mixed methods study protocol
  • Home monitoring by pulse oximetry of primary care patients with COVID-19: a pilot randomised controlled trial
  • The Colorectal cancer RISk Prediction (CRISP) trial: a randomised controlled trial of a decision support tool for risk-stratified colorectal cancer screening
  • Finagles laws of information: lessons learnt evaluating a complex health intervention in Nigeria
  • Application of complexity theory in health and social care research: a scoping review
  • Evaluating a clinical ethics committee (CEC) implementation process in an oncological research hospital: protocol for a process evaluation study using normalisation process theory (EvaCEC)
  • Earlier cancer diagnosis in primary care: a feasibility economic analysis of ThinkCancer!
  • Testing and refining middle-range theory in evaluations of public-health interventions: evidence from recent systematic reviews and trials
  • School lives of adolescent school students living with chronic physical health conditions: a qualitative evidence synthesis
  • Study protocol for PREPARE: a phase II feasibility/safety randomised controlled trial on PeRiopErative Penicillin AlleRgy TEsting
  • Effectiveness of synchronous teleconsultation for patients with type 2 diabetes mellitus: a systematic review and meta-analysis
  • Patient perspectives on, and effects of, medication management in geriatric fallers (the EMMA study): protocol for a mixed-methods pre-post study
  • Effect of ICU care bundles on long-term patient-relevant outcomes: a scoping review
  • Understanding how primary care practitioners can be supported to recognise, screen and initially diagnose oropharyngeal dysphagia: protocol for a behavioural science realist review
  • Interventions to reintroduce or increase assisted vaginal births: a systematic review of the literature
  • Home monitoring by pulse oximetry of primary care patients with COVID-19: a pilot randomised controlled trial
  • Implementing complex interventions to mitigate burnout among qualified healthcare professionals: a realist review protocol
  • Evaluating the implementation and impact of a new model of care for integrating children and young peoples acute mental healthcare in a paediatric setting: a protocol for a realist, mixed-methods approach
  • Cessation of smoking trial in the emergency department (CoSTED): protocol for a multicentre randomised controlled trial
  • (How) Do we theorize? A focused mapping review and synthesis of theoretical nursing research in the German-speaking area of Europe
  • Responsive evaluation: an innovative evaluation methodology for workplace health promotion interventions
  • Implementation and perceived impact of the SWAN model of end-of-life and bereavement care: a realist evaluation
  • Staff experiences of diabetes care in residential care facilities for people with severe disabilities in Denmark: a mixed-methods assessment of access to screening for diabetes complications
  • Feasibility and acceptability of a paearahi (Indigenous Whanau Ora navigator) intervention for unintentional injury prevention for older Maori: non-randomised, non-comparator trial study protocol
  • Introduction to the development of complex interventions
  • Can web-based implementation interventions improve physician early diagnosis of cerebral palsy? Protocol for a 3-arm parallel superiority randomised controlled trial and cost-consequence analysis comparing adaptive and non-adaptive virtual patient instructional designs with control to evaluate effectiveness on physician behaviour, diagnostic skills and patient outcomes
  • Complex multidisciplinary intervention to improve Initial Medication Adherence to cardiovascular disease and diabetes treatments in primary care (the IMA-cRCT study): mixed-methods process evaluation protocol
  • How to co-design a health literacy-informed intervention based on a needs assessment study in chronic obstructive pulmonary disease
  • Effect of social prescribing link workers on health outcomes and costs for adults in primary care and community settings: a systematic review
  • HABIT: Health visitors delivering Advice in Britain on Infant Toothbrushing - an early-phase feasibility study of a complex oral health intervention
  • Interventions Promoting Recovery from Depression for Patients Transitioning from Outpatient Mental Health Services to Primary Care: Protocol for a Scoping Review
  • Evaluation of implementation and effects of a health-promoting sports club intervention using a mixed-method design: PROSCeSS protocol
  • Effectiveness of the Perceive, Recall, Plan and Perform intervention for persons with brain injury in community-based rehabilitation: protocol for a single-case experimental design with multiple baselines
  • DEVELOPMENT OF A COMPLEX INTERVENTION PACKAGE FOR DENGUE PREVENTION
  • Realist inquiry into Maternity care @ a Distance (ARM@DA): realist review protocol
  • Prioritising the content and delivery of a work-focused intervention for women with breast cancer using the nominal group technique
  • A search for relevant contextual factors in intervention studies: a stepwise approach with online information
  • Evaluating effects of the structural reform of outpatient psychotherapy for patients with mental disorders in Germany: comparing patients with and without comorbid chronic physical condition - rationale and study protocol of the ES-RiP project
  • A new framework for developing and evaluating complex interventions: Webinar review and reflections on the updated MRC guidance
  • Follow-up after gestational diabetes: a qualitative study of perspectives from general practices
  • Process evaluation of complex interventions in non-communicable and neglected tropical diseases in low- and middle-income countries: a scoping review
  • Reporting dose in complex self-management support interventions for long-term conditions: is it defined by researchers and received by participants? A systematic review
  • Novel device for assisted vaginal birth: using integrated qualitative case study methodology to optimise Odon Device use within a feasibility study in a maternity unit in the Southwest of England
  • The Shared Safety Net Action Plan (SSNAP): a co-designed intervention to reduce delays in cancer diagnosis
  • Protocol for a qualitative study to explore acceptability, barriers and facilitators of the implementation of new teleophthalmology technologies between community optometry practices and hospital eye services
  • Protocol for a process evaluation: face-to-face physiotherapy compared with a supported home exercise programme for the management of musculoskeletal conditions: the REFORM trial
  • Protocol for an intervention development and pilot implementation evaluation study of an e-health solution to improve newborn care quality and survival in two low-resource settings, Malawi and Zimbabwe: Neotree
  • Tailoring lipid management interventions to reduce inequalities in cardiovascular disease risk management in primary care for deprived communities in Northern England: a mixed-methods intervention development protocol
  • Youth researchers academy: a report on an innovative research training programme for young people in Zimbabwe
  • Psychological interventions for inflammatory bowel disease: a systematic review and component network meta-analysis protocol
  • Informing behaviour change intervention design using systematic review with Bayesian meta-analysis: physical activity in heart failure
  • Systematic review of the effectiveness of non-pharmacological interventions used to treat adults with inducible laryngeal obstruction
  • Designing an online intervention for adults with addictive eating: a qualitative integrated knowledge translation approach
  • Supporting families managing childhood eczema: developing and optimising eczema care online using qualitative research
  • Childhood eczema: paths to optimisation of management
  • Internet-based support for informal caregivers to individuals with head and neck cancer (Carer eSupport): a study protocol for the development and feasibility testing of a complex online intervention
  • Guidance relevant to the reporting of health equity in observational research: a scoping review protocol
Back to top