Letters NICE on lipid modification

NICE has overestimated cardiovascular risk

BMJ 2008; 336 doi: https://doi.org/10.1136/bmj.39605.518287.3A (Published 12 June 2008) Cite this as: BMJ 2008;336:1323
  1. Richard G Richards, assistant director of public health
  1. 1Derbyshire County Primary Care Trust, Babington Hospital, Belper DE56 1WH
  1. richard.richards{at}derbyshirecountypct.nhs.uk

The National Institute for Health and Clinical Excellence (NICE) has recommended that cardiovascular risk should be calculated by adding the risks of coronary heart disease and stroke derived from the Framingham study.1 This is an elementary epidemiological error as the two risks are related. The effect is to overestimate risk.

The Framingham study has its limitations. UK data have been …

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