Letters Leprosy chemoprophylaxis

What’s the need?

BMJ 2008; 336 doi: https://doi.org/10.1136/bmj.39549.445521.3A (Published 17 April 2008) Cite this as: BMJ 2008;336:847
  1. Mohammad M Rahman, residency applicant
  1. 1Brampton, ON, Canada L7A 1V7
  1. md.mrahman{at}sympatico.ca

The study reported by Moet et al found benefit at two years after rifampicin, but did not find any significant difference between rifampicin chemoprophylaxis and placebo treatment in the third and fourth years after rifampicin treatment.1 Mycobacterium leprae multiplies very slowly, and the incubation period of leprosy is about five years but can be up to 20 years (www.who.int/mediacentre/factsheets/fs101/en/index.html). Whether …

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