Research into HIV vaccines needs to change direction

BMJ 2008; 336 doi: (Published 03 April 2008) Cite this as: BMJ 2008;336:743
  1. Bob Roehr
  1. 1Washington, DC

HIV vaccine research should turn away from clinical trials and refocus instead on more basic studies, a meeting in Bethesda, Maryland, decided last week.

“Despite hundreds and hundreds of millions of dollars, the reality in 2008 is that an HIV vaccine clearly remains beyond our grasp,” said Warner Greene, director of the Gladstone Institute of Virology and Immunology at the University of California, San Francisco, at the opening session.

Last autumn a second candidate for an HIV vaccine failed. Although few expected it to protect against infection, the hope had been that it might bolster immune defences and result …

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