Follow-up of children who survive cancerBMJ 2008; 336 doi: https://doi.org/10.1136/bmj.39490.692627.80 (Published 03 April 2008) Cite this as: BMJ 2008;336:732
- Meriel Jenney, consultant paediatric oncologist1,
- Gill Levitt, consultant in paediatric oncology and late effects2
- 1Children’s Hospital for Wales, Cardiff CF14 4XW
- 2Great Ormond Street Hospital, London WC1N 3JH
More than three quarters of children with cancer survive into adulthood, but cure is not the end of their journey. At least 60% have substantial morbidities as a result of their curative treatment. Most adults who survive cancer are discharged from active follow-up at five years, but historically children have been followed up for life; this is becoming unsustainable. A review published in the BMJ more than five years ago explored strategies for follow-up of children who have survived cancer.1 Has anything changed since then?
Two large epidemiological studies—one in the United States and the other in the United Kingdom—have since been published.2 3 More than 10 000 survivors in 26 centres participated in the US study, which found that 62% of survivors have some late effects of treatment (common terminology criteria for adverse events (version 3) grade 1-5), with 27% having severe or life threatening conditions (grade 3-5).4 Data …