BMJ 2008; 336 doi: https://doi.org/10.1136/bmj.39499.672361.80 (Published 28 February 2008) Cite this as: BMJ 2008;336:514

Snorting insulin appears to improve cognitive function in early Alzheimer’s disease. It takes less than 15 minutes for insulin-like peptides to follow extracellular pathways to the brain after intranasal administration. A pilot study of 25 patients randomly assigned to receive placebo or insulin found that although blood glucose concentrations were unchanged, patients who were given insulin retained more verbal information after a delay and had better concentration than those given placebo (Neurology 2008;70:440-8 doi: 10.1212/01.WNL.0000265401.62434.36).

Depression and anxiety account for more of the variance in quality of life measures in patients with sickle cell disease than haemoglobin type (Psychosomatic Medicine 2008;70:192-6 doi: 10.1097/PSY.0b013e31815ff5c5). Of 232 adults with the condition who completed month long diaries, 27.6% were depressed and 6.5% had an anxiety disorder. Depressed patients had significantly more days of pain than non-depressed patients, and when in pain on non-crisis days, patients who were depressed or anxious had more pain, distress, and functional interference.

Moisturising body milk caused a severe outbreak of Burkholderia cepacia in an 18 bed intensive care unit …

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