Letters Osteoarthritis of the knee

Topical NSAIDs have unknown effectiveness

BMJ 2008; 336 doi: https://doi.org/10.1136/bmj.39486.438426.3A (Published 14 February 2008) Cite this as: BMJ 2008;336:344
  1. Peter C Gøtzsche, director
  1. 1Nordic Cochrane Centre, Rigshospitalet, Department 3343, DK-2100 Copenhagen Ø, Denmark
  1. pcg{at}cochrane.dk

    Dieppe claimed in an editorial about osteoarthritis that topical non-steroidal anti-inflammatory drugs (NSAIDs) are as effective as oral NSAIDs.1 He refers to a report from the National Institute for Health and Clinical Excellence (NICE), which describes two meta-analyses. He notes that the authors assessed the trials for quality, but the 424 page report says nothing about that quality. The …

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